L1CAM (L1 cell adhesion molecule)
نویسندگان
چکیده
منابع مشابه
L1 Cell Adhesion Molecule (L1CAM) Promotes Tumorigenicity and Metastatic Potential in Non-Small-Cell Lung Cancer
Running Title: L1CAM in non-small cell lung cancer Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Abstract Purpose: Non-small-cell lung cancer (NSCLC) is a highly metastatic cancer with limited treatment options, thus requiring development of novel targeted therapies. Our group previously identified L1 cell adhesion molecule (L1CAM) express...
متن کاملL1 cell adhesion molecule (L1CAM) is a strong predictor for locoregional recurrences in cervical cancer
Background L1 cell adhesion molecule (L1CAM) has been shown to be a prognostic marker in various cancer types, and has been suggested to play a role in epithelial mesenchymal transition (EMT). Here, we determined the prognostic significance of L1CAM in cervical cancer and its association with vimentin expression on tumor cells, indicative of EMT. Methods Formalin-fixed, paraffin-embedded prim...
متن کاملL1 cell adhesion molecule (L1CAM) as a pathogenetic factor in endometriosis.
BACKGROUND Endometriosis is a benign and progressive disease with a high prevalence. Women with endometriosis, especially with atypical endometriosis, have a higher probability for developing ovarian cancer compared with women without endometriosis. The L1 cell adhesion molecule (L1CAM) is over expressed in ovarian and endometrial carcinomas and is associated with a bad prognosis. Here, we have...
متن کاملPrognostic value and clinicopathologic characteristics of L1 cell adhesion molecule (L1CAM) in a large series of vulvar squamous cell carcinomas
BACKGROUND Vulvar cancer treatment is mostly curative, but also has high morbidity rates. In a search for markers that can identify patients at risk of metastases, we investigated the prognostic value of L1-cell adhesion molecule (L1CAM) in large series of vulvar squamous cell carcinomas (VSCCs). L1CAM promotes cell motility and is an emerging prognostic factor for metastasis in many cancer sub...
متن کاملImpact of L1 Cell Adhesion Molecule on Macrophage Activation
INTRODUCTION Nowadays, per research study, around 5.6 million people around the United States suffer from paralysis [1]. There are many reasons that contribute to paralysis: stroke, spinal cord injuries, multiple sclerosis and so on. Patients who suffer from paralysis lose partial or fully sensory function and motor intention. Although paralysis is not life-threatening for most of the patients,...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2011
ISSN: 1768-3262
DOI: 10.4267/2042/44612